Short description
Broadly neutralizing antibodies are effective against multiple strains of a certain pathogen and are of particular interest in the treatment of HIV.
Synonyms
bNAbs

Detailed description

A broadly neutralizing antibody neutralizes the effect of the antigen to which it binds and thereby supports the immune defense. What is special about these broadly neutralizing antibodies is that they bind to conserved pathogen surface structures. These targeted structures do not change much even if the pathogen is modified by mutation. Broadly neutralizing antibodies have been found against HIV and influenza virus. They could in the future play a role in the development of a vaccine against these viruses.