Malaria

Malaria wird durch Mücken übertragen. Eine vorbeugende Impfung gibt es nicht. © CDC/James Gathany

Despite a multitude of actions taken to eradicate malaria, the disease still remains one of the top killers of African children under 5 years of age. Although a hot topic in research for many years, an efficient vaccine for prevention has not been brought to the market yet, and the spread of resistance to the drugs currently administered makes it painfully clear that we need new medications to provide effective therapy for all target groups. Regional differences in parasite and human populations as well as co-infections are further obstacles impeding an efficient and correct treatment of patients. A continuous effort in epidemiological research is required to keep knowledge of current parasite distributions up-to-date as a prerequisite for efficient intervention design. The mission of the Thematic Translational Unit "Malaria" is to fight malaria with preventive and therapeutic measures simultaneously, using disease modelling to optimize antimalarial interventions in Africa.

Research Areas

  • Prevention - test and optimize promising vaccine candidates
  • Treatment - rapidly translate novel promising parasite inhibitors from preclinical to clinical development
  • Epidemiology - fully understand local parasite distributions for planning new antimalarial interventions in endemic areas

Participating Focus Sites

Tübingen
Heidelberg
Hamburg-Lübeck-Borstel-Riems

Contact

Interview with Peter Kremsner, TTU "Malaria" [in German]

Coordinator
Peter Kremsner, Universität & Universitätsklinikum Tübingen

Co-Coordinators
Michael Lanzer, Universität & Universitätsklinikum Heidelberg
Jürgen May, Bernhard-Nocht-Institut für Tropenmedizin

Project manager
Maddalena di Lellis