Enterococcus faecium is intrinsically resistant to many antibiotics and can cause difficult-to-treat infections, especially in immunocompromised and other vulnerable patients. Vancomycin-resistant E. faecium (VRE) strains are especially problematic because vancomycin cannot be used to treat these infections. Resistance is mediated by the VanA or VanB enzyme complexes, which neutralize the [...]

By applying innovative diagnostic methods such as rapid point-of-care tests, multi-omics technologies as well as novel predictive models, clinical management and thus most likely treatment outcomes can be improved. In addition to the high information content of these new methods, the prompt availability of the results as well as the [...]