Welcome to the DZIF -

the German Center for Infection Research

Research Areas

Gastrointestinal Infections

Hepatitis

HIV

Infections of the immunocompromised Host

Healthcare-associated and Antibiotic-resistant bacterial Infections

Malaria

Emerging Infections

Novel Antibiotics

Tuberculosis

News

Hepatitis B virions (orange coloured)
© CDC/Dr. Erskine Palmer

Checkmate for hepatitis B viruses in the liver

Laboratory-synthesized lugdunin
© Universität Tübingen/Sebastian N. Wirtz

Antibiotic Produced by the Microbiome kills Bacteria by Disturbing Energy Metabolism

A research team from the Universities of Tübingen and Göttingen as well as from the German Center for Infection Research has investigated the mode of action of a new class of antibiotics that is
Helicobacter pylori
© HZI/ M. Rohde

Helicobacter pylori: Signs of selection in the stomach

Helicobacter pylori , a globally distributed gastric bacterium, is genetically highly adaptable. The DZIF team of Professor Sebastian Suerbaum at LMU has now characterized its population structure in
Aedes albopictus
© cdc_James Gathany

Early Dengue Virus Infection could “defuse” Zika Virus

The Zika virus outbreak in Latin America has affected over 60 million people up to now. The infection can have potentially fatal consequences for pregnant women and their unborn children: many
Mucispirillum
© B. Stecher

Gut Microbe helps thwart Salmonella

Salmonella infections can have serious consequences for certain high-risk groups, such as young children, the elderly and individuals whose immune systems are functionally compromised. Most people
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Research in Focus

Bonn - Cologne

Neglected Tropical Diseases

Currently, approximately one billion people worldwide are at risk of developing an inability to work or blindness, becoming maimed or dying due to neglected tropical diseases (NTD). NTDs include river blindness, dengue fever, sleeping sickness, snakebites and leprosy, only to name a few known examples of this diverse group of [...]

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Hamburg - Lübeck - Borstel - Riems

Clinical Tuberculosis Centre

The Clinical Tuberculosis Centre provides the expertise and infrastructure for the optimisation, prevention, diagnosis and treatment of tuberculosis (TB) as well as for translating research results into clinical practice. The main objectives of the Clinical Tuberculosis Centre include coordinating clinical research activities involving the DZIF TB cohort. This cohort includes [...]

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Tübingen

New strategies for specific eradication of Staphylococcus aureus

In this project, the scientists develop genetically engineered phage lysins and specific bacteriocins for the elimination of hospital germs such as Staphylococcus aureus, they clarify mechanisms of potential resistance mechanisms, and they analyse whether broad-spectrum or specifically acting agents have a more effective and lasting effect on colonization by S. [...]

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Hanover - Brunswick

Preclinical development of Amidochelocardins

The challenge of antibiotic drug development today is the discovery and optimisation of novel bioactive compounds that do not show cross-resistances with clinically applied antibiotics, ideally due to a novel mode of action (MoA) which adresses unexploited microbial targets. In the case of chelocardin, this antibiotic substance was identified several [...]

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Our Partner Sites

Munich Tuebingen Heidelberg Gießen – Marburg – Langen Bonn – Cologne Hanover – Brunswick Hamburg – Lubeck Borstel – Riems
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