Welcome to the DZIF -

the German Center for Infection Research

Research Areas

DZIF is doing research in nine areas:

Community-Acquired Infections at Mucosal Interfaces

Hepatitis

HIV

Infections of the Immunocompromised Host

Healthcare-Associated Infections

Malaria and Neglected Tropical Diseases

Emerging Infections

Novel Antibiotics

Tuberculosis

News

News and Press Releases:

Preisträger des "Tu Youyou Awards 2024: DZIF-Forscher Rolf Müller
© HIPS/Dietze

Award for outstanding achievements in natural product research

Map of South America with areas coloured according to the risk of infection with Oropouche virus.
© Charité/Anna Frühauf

A mysterious pathogen: Oropouche virus more common in Latin America than previously thought

Like the dengue and Zika viruses, Oropouche virus causes a febrile illness. There are recent indications that infections during pregnancy can cause damage to unborn babies. Researchers at Charité –
Red-coloured rod-shaped bacteria in an electron micrograph.
© CDC/Alissa Eckert; James Archer

Multidrug-resistant bacteria: development of new antibiotics

The German Research Foundation (DFG) and the French Agence National de la Recherche (ANR) are now funding the project "Characterization of novel natural product binding sites in the DNA gyrase of
3D model of the molecular structure of the pathoblocker HilD
© Universität Tübingen/Leon Kokkoliadis, CC-BY-ND

New pathoblocker to stop Salmonella infection early

Pathogenic strains of Salmonella inject effector proteins into the cells of the gastrointestinal tract to invade and multiply within them. The bacteria are usually ingested with contaminated food
A member of the RHINO team leans over a table with laboratory and test materials set up in a village in Tanzania.
© LMU Klinikum München/Inge Kroidl

Eliminating worm infections as a key strategy for HIV/AIDS prevention

Researchers from the Institute of Infectious Diseases and Tropical Medicine at the LMU University Hospital Munich, the National Institute for Medical Research (NIMR) – Mbeya Medical Research Center
All news

What is the DZIF? Find out more in our

DZIF movie

More than 700 people work at the DZIF with the common goal of translating basic research into clinical practice. The well-being of the patient is our primary focus. Get more insight into the DZIF in our new DZIF film:

Watch the movie
A GIF animation with clips from the DZIF film.

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Research in Focus

Hamburg - Lübeck - Borstel - Riems

Clinical Tuberculosis Center

The Clinical Tuberculosis Center provides the expertise and infrastructure for the optimization, prevention, diagnosis, and treatment of tuberculosis (TB) as well as for translating research results into clinical practice. The main objectives of the Clinical Tuberculosis Center include coordinating clinical research activities involving the DZIF TB cohort. This cohort includes [...]

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Hannover - Braunschweig | Heidelberg | München | Tübingen

Transplant Cohort

Medical data and biological samples obtained from transplant patients are collected and managed across Germany with the help of the DZIF Transplant Cohort. The data and samples form the basis of scientific studies which investigate the connections between numerous factors influencing an organ’s susceptibility to infection and organ function. In [...]

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Hannover - Braunschweig

Preclinical development of Amidochelocardins

The challenge of antibiotic drug development today is the discovery and optimisation of novel bioactive compounds that do not show cross-resistances with clinically applied antibiotics, ideally due to a novel mode of action (MoA) which adresses unexploited microbial targets. In the case of chelocardin, this antibiotic substance was identified several [...]

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Tübingen

New strategies for specific eradication of Staphylococcus aureus

In this project, the scientists develop genetically engineered phage lysins and specific bacteriocins for the elimination of hospital germs such as Staphylococcus aureus, they clarify mechanisms of potential resistance mechanisms, and they analyse whether broad-spectrum or specifically acting agents have a more effective and lasting effect on colonization by [...]

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Our Partner Sites

Location

Bonn - Köln

Research areas
Contact person
Prof Achim Hörauf: Coordinator of the consortium "Neglected tropical diseases" at DZIF.

Prof. Dr. Achim Hörauf

University Hospital Bonn
Deputy Partner Site Speaker Bonn-Köln
Deputy Coordinator Malaria and Neglected Tropical Diseases
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Location

Hamburg - Lübeck - Borstel - Riems

Research areas
Contact person
More about this location
Location

Hannover - Braunschweig

Research areas
Contact person
Silke Hartmann

Dr. Silke Hartmann

Hannover Medical School
Partner Site Manager Hannover - Braunschweig
Project Manager Community-Acquired Infections at Mucosal Interfaces
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Location

Heidelberg

Research areas
Contact person
Stephan Urban

Prof. Dr. Stephan Urban

Heidelberg University
Deputy Coordinator Hepatitis
DZIF Professor "Translational Virology"
Partner Site Speaker Heidelberg
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München Tübingen Heidelberg Giessen – Marburg – Langen Bonn – Köln Hannover – Braunschweig Hamburg – Lübeck Borstel – Riems
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Databases- & Biobanks 2023