Welcome to the DZIF -

the German Center for Infection Research

Gastrointestinal Infections

Hepatitis

HIV

Infections of the Immunocompromised Host

Healthcare-Associated and Antibiotic-Resistant Bacterial Infections

Malaria and Neglected Tropical Diseases

Emerging Infections

Novel Antibiotics

Tuberculosis

May 23 2023

Apply now: DZIF Prize for Translational Infection Research 2023

May 15 2023

Infection with common cold coronaviruses can trigger broad cross-immunity against SARS-CoV-2 proteins

Researchers at the University Medical Center Hamburg-Eppendorf have demonstrated cross-reactive immune responses to another protein besides the spike protein. The research team found a

May 9 2023

European initiative INCATE: Phase II funding of a start-up for the development of antimicrobial proteins

The incubator INCATE (INCubator for Antibacterial Therapies in Europe) was founded by a consortium of academic institutions—including the German Center for Infection Research (DZIF)—and industrial

Schematic representation of two agar plates, each with a paper strip. On the left plate, an inhibition zone can be seen around the paper strip.

May 9 2023

Targeting resistance to a crucial reserve antibiotic

is a last-line reserve antibiotic for the treatment of infections caused by extremely multidrug-resistant (XDR) bacteria. The recent emergence and global spread of the mobile

Victoria Ingham in the lab holding a suction flask full of Anopheles mosquitoes.

Apr 28 2023

DZIF malaria researcher gains funding

Dr. Victoria Ingham from Heidelberg University Hospital and the German Center for Infection Research (DZIF) is investigating the potential dual effect of a new insecticide for mosquito nets. The

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The DZIF at a glance:

United against infections

Learn more about the German Center for Infection Research (DZIF) and the four grand infectious disease challenges of our time:

DZIF portrait page

GIF animation of grand challenges, research areas and infrastructures within DZIF

Video

Das zentrale Bioprobenregister im DZIF

Video

DZIF Annual Report 2021—Detail of the cover page

pdf (3.65 MB)

Blutkulturflaschen

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Find Media Content

Hannover - Braunschweig | Heidelberg | München | Tübingen

Medical data and biological samples obtained from transplant patients are collected and managed across Germany with the help of the DZIF Transplant Cohort. The data and samples form the basis of scientific studies which investigate the connections between numerous factors influencing an organ’s susceptibility to infection and organ function. In [...]

Hamburg - Lübeck - Borstel - Riems

Clinical Tuberculosis Centre

The Clinical Tuberculosis Centre provides the expertise and infrastructure for the optimisation, prevention, diagnosis and treatment of tuberculosis (TB) as well as for translating research results into clinical practice. The main objectives of the Clinical Tuberculosis Centre include coordinating clinical research activities involving the DZIF TB cohort. This cohort includes [...]

Tübingen

New strategies for specific eradication of Staphylococcus aureus

In this project, the scientists develop genetically engineered phage lysins and specific bacteriocins for the elimination of hospital germs such as Staphylococcus aureus, they clarify mechanisms of potential resistance mechanisms, and they analyse whether broad-spectrum or specifically acting agents have a more effective and lasting effect on colonization by [...]

Hannover - Braunschweig

Preclinical development of Amidochelocardins

The challenge of antibiotic drug development today is the discovery and optimisation of novel bioactive compounds that do not show cross-resistances with clinically applied antibiotics, ideally due to a novel mode of action (MoA) which adresses unexploited microbial targets. In the case of chelocardin, this antibiotic substance was identified several [...]