Welcome to the DZIF -

the German Center for Infection Research

Research Areas

DZIF is doing research in nine areas:

Gastrointestinal Infections

Hepatitis

HIV

Infections of the Immunocompromised Host

Healthcare-Associated and Antibiotic-Resistant Bacterial Infections

Malaria and Neglected Tropical Diseases

Emerging Infections

Novel Antibiotics

Tuberculosis

News

News and Press Releases:

Logo of World NTD Day, showing a stylized sun and the text lines "30 January - World NTD Day - Neglected Tropical Diseases" in white on a red background
© World NTD Day

30 January – World Neglected Tropical Diseases Day

Anna Hirsch
© HIPS/Dietze

ERC Grant for Anna Hirsch

Prof Anna Hirsch from the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) has now succeeded in acquiring a coveted European Research Council (ERC) grant for the second time. Under the
Enterobacteriaceae
© cdc_Illustration: Stephanie Rossow

Targeted test for antibiotic resistance in clinical Enterobacter species

Bacteria of the genus Enterobacter are among the most dangerous bacteria associated with hospital infections worldwide. Some of their representatives are highly resistant to commonly used antibiotics
Fluorescence micrograph of blue-stained cells on a black background. In the left half of the image, green-stained Lec A-proteins bind to the cells. In the right half of the image, only blue-stained cells are visible.
© Francesca Rosato, Dorina Reith/University of Freiburg

Sugar-based inhibitors disarm the pathogen Pseudomonas aeruginosa

The hospital germ Pseudomonas aeruginosa forms biofilms, a kind of mucus layer, to protect itself from attack by the immune system or antibiotics. To form this sticky layer, as well as to successfully
Staphylococcus aureus
© NIAID

Saarbrücken antibiotics project funded by INCATE incubator

With INCATE (INCubator for Antibacterial Therapies in Europe), the German Center for Infection Research (DZIF) has participated in the foundation of a European initiative to take up the fight against
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The DZIF at a glance:

United against infections

Learn more about the German Center for Infection Research (DZIF) and the four grand infectious disease challenges of our time:

https://www.dzif.de/en/portrait
GIF animation of grand challenges, research areas and infrastructures within DZIF

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Research in Focus

Hamburg - Lübeck - Borstel - Riems

Clinical Tuberculosis Centre

The Clinical Tuberculosis Centre provides the expertise and infrastructure for the optimisation, prevention, diagnosis and treatment of tuberculosis (TB) as well as for translating research results into clinical practice. The main objectives of the Clinical Tuberculosis Centre include coordinating clinical research activities involving the DZIF TB cohort. This cohort includes [...]

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Hannover - Braunschweig | Heidelberg | München | Tübingen

Transplant Cohort

Medical data and biological samples obtained from transplant patients are collected and managed across Germany with the help of the DZIF Transplant Cohort. The data and samples form the basis of scientific studies which investigate the connections between numerous factors influencing an organ’s susceptibility to infection and organ function. In [...]

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Hannover - Braunschweig

Preclinical development of Amidochelocardins

The challenge of antibiotic drug development today is the discovery and optimisation of novel bioactive compounds that do not show cross-resistances with clinically applied antibiotics, ideally due to a novel mode of action (MoA) which adresses unexploited microbial targets. In the case of chelocardin, this antibiotic substance was identified several [...]

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Tübingen

New strategies for specific eradication of Staphylococcus aureus

In this project, the scientists develop genetically engineered phage lysins and specific bacteriocins for the elimination of hospital germs such as Staphylococcus aureus, they clarify mechanisms of potential resistance mechanisms, and they analyse whether broad-spectrum or specifically acting agents have a more effective and lasting effect on colonization by S [...]

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Our Partner Sites

München Tübingen Heidelberg Giessen – Marburg – Langen Bonn – Köln Hannover – Braunschweig Hamburg – Lübeck Borstel – Riems
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Databases- & Biobanks 2021