Welcome to the DZIF -

the German Center for Infection Research

Research Areas

DZIF is doing research in nine areas:

Community-Acquired Infections at Mucosal Interfaces

Hepatitis

HIV

Infections of the Immunocompromised Host

Healthcare-Associated Infections

Malaria and Neglected Tropical Diseases

Emerging Infections

Novel Antibiotics

Tuberculosis

News

News and Press Releases:

Map of South America with areas coloured according to the risk of infection with Oropouche virus.
© Charité/Anna Frühauf

A mysterious pathogen: Oropouche virus more common in Latin America than previously thought

3D model of the molecular structure of the pathoblocker HilD
© Universität Tübingen/Leon Kokkoliadis, CC-BY-ND

New pathoblocker to stop Salmonella infection early

Pathogenic strains of Salmonella inject effector proteins into the cells of the gastrointestinal tract to invade and multiply within them. The bacteria are usually ingested with contaminated food
A member of the RHINO team leans over a table with laboratory and test materials set up in a village in Tanzania.
© LMU Klinikum München/Inge Kroidl

Eliminating worm infections as a key strategy for HIV/AIDS prevention

Researchers from the Institute of Infectious Diseases and Tropical Medicine at the LMU University Hospital Munich, the National Institute for Medical Research (NIMR) – Mbeya Medical Research Center
Performing rapid antigen tests in Colombia
© Charité/Edmilson de Oliveira Filho

Lessons learned from the COVID-19 pandemic

The COVID-19 pandemic exposed critical deficiencies in the global health system and provides important lessons to improve preparedness for future emergencies. A case in point is Latin America, where
Paper model of the human intestine, held by a person with a doctor's coat and stethoscope. This is a stock image.
© Adobe Stock/Elena Nechaeva

Gut microbiome as a predictive factor for kidney rejection?

Kidneys are the most transplanted organ in Germany. According to the German Organ Transplantation Foundation, a total of 1,514 kidneys were transplanted after post-mortem organ donation in 2023, out
All news

World Malaria Day on the 25th of April

End malaria

"Malaria ends with us. Reinvest, rethink, reignite" is the motto of World Malaria Day 2025. At the DZIF, we are developing new strategies to combat the disease, including innovative drugs and improved diagnostics. We are also focusing on the role of mosquitoes as vectors of malaria pathogens.

Malaria research at the DZIF
The picture shows an abstracted mosquito. Below is written in blue lettering: World Malaria Day; 25 April. The picture is outlined in turquoise.

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Research in Focus

Hannover - Braunschweig | Heidelberg | München | Tübingen

Transplant Cohort

Medical data and biological samples obtained from transplant patients are collected and managed across Germany with the help of the DZIF Transplant Cohort. The data and samples form the basis of scientific studies which investigate the connections between numerous factors influencing an organ’s susceptibility to infection and organ function. In [...]

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Hamburg - Lübeck - Borstel - Riems

Clinical Tuberculosis Centre

The Clinical Tuberculosis Centre provides the expertise and infrastructure for the optimisation, prevention, diagnosis and treatment of tuberculosis (TB) as well as for translating research results into clinical practice. The main objectives of the Clinical Tuberculosis Centre include coordinating clinical research activities involving the DZIF TB cohort. This cohort includes [...]

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Tübingen

New strategies for specific eradication of Staphylococcus aureus

In this project, the scientists develop genetically engineered phage lysins and specific bacteriocins for the elimination of hospital germs such as Staphylococcus aureus, they clarify mechanisms of potential resistance mechanisms, and they analyse whether broad-spectrum or specifically acting agents have a more effective and lasting effect on colonization by [...]

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Hannover - Braunschweig

Preclinical development of Amidochelocardins

The challenge of antibiotic drug development today is the discovery and optimisation of novel bioactive compounds that do not show cross-resistances with clinically applied antibiotics, ideally due to a novel mode of action (MoA) which adresses unexploited microbial targets. In the case of chelocardin, this antibiotic substance was identified several [...]

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Our Partner Sites

Location

Hannover - Braunschweig

Research areas
Contact person
Silke Hartmann

Dr. Silke Hartmann

Hannover Medical School
Partner Site Manager Hannover - Braunschweig
Project Manager Community-Acquired Infections at Mucosal Interfaces
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Location

Heidelberg

Research areas
Contact person
Stephan Urban

Prof. Dr. Stephan Urban

Heidelberg University
Deputy Coordinator Hepatitis
DZIF Professor "Translational Virology"
Partner Site Speaker Heidelberg
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Location

Hamburg - Lübeck - Borstel - Riems

Research areas
Contact person
More about this location
Location

Bonn - Köln

Research areas
Contact person
Prof Achim Hörauf: Coordinator of the consortium "Neglected tropical diseases" at DZIF.

Prof. Dr. Achim Hörauf

University Hospital Bonn
Deputy Partner Site Speaker Bonn-Köln
Deputy Coordinator Malaria and Neglected Tropical Diseases
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München Tübingen Heidelberg Giessen – Marburg – Langen Bonn – Köln Hannover – Braunschweig Hamburg – Lübeck Borstel – Riems
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Databases- & Biobanks 2023