Patients colonized with vancomycin-resistant enterococci (VRE)—particularly immunocompromised patients—are at increased risk of developing subsequent VRE infections. Repeated antibiotic therapies are not an option for decolonization in patients receiving immunosuppressive therapy, as antibiotic-induced selection pressure may promote the further spread of multidrug-resistant enterococci. Effective and sustainable strategies for reducing or eradicating [...]

Major abdominal surgery in particular is associated with high postoperative infection rates. Despite well-established surveillance systems for surgical wound infections, there is a lack of comprehensive reporting on infectious complications and the impact of the use of anti-infectives during and after surgery. The TIARA project aims to close this knowledge [...]

Recent studies show that there has been an increasing spread of vancomycin-resistant enterococci (VRE) in hospital patients in Germany in recent years. Enterococci are abundant in the intestines of humans (and animals) and are generally only slightly pathogenic. However, infections caused by these resistant pathogens pose an immediate threat to [...]