Enterococcus faecium is intrinsically resistant to many antibiotics and can cause difficult-to-treat infections, especially in immunocompromised and other vulnerable patients. Vancomycin-resistant E. faecium (VRE) strains are especially problematic because vancomycin cannot be used to treat these infections. Resistance is mediated by the VanA or VanB enzyme complexes, which neutralize the [...]
