Fabian Grein's research group is investigating new targets for antibiotics against staphylococci. Staphylococcus aureus causes a broad range of infections, in particular soft tissue, bone and skin infections, but also bloodstream infections and very often postoperative wound infections. Since this pathogen has special abilities to quickly develop spontaneous or acquired [...]
In this project, the scientists have developed a monoclonal antibody directed against a resistance protein that is crucial for the virulence, i.e. infectious effect, of Staphylococcus aureus. The monoclonal antibody can restore the body's own defence and thus make the bacteria vulnerable to antibiotics.