Heterovirulence | German Center for Infection Research

Short description

Heterovirulence refers to the presence of subpopulations within a genetically very similar pathogen population that differ in their ability to cause disease.

Synonyms

Virulence heterogeneity

Virulence variation

Heterogeneous virulence

Detailed description

Heterovirulence refers to the presence of subpopulations within a genetically very similar or identical pathogen population that differ in their ability to cause disease. These subpopulations exhibit varying degrees of virulence and may differ, for example, in how well they colonize the host, evade the immune system, or damage tissue. Heterovirulence can increase the adaptability of pathogens and influence the course of an infection.

Mar 2023

EBioMedicine

Phylogroup-specific variation shapes the clustering of antimicrobial resistance genes and defence systems across regions of genome plasticity in Pseudomonas aeruginosa

Autoren

Botelho J et al.

Bridging Topic: Global Health and Climate Change

Improved health and public health adaptation strategies are essential to prepare for increased risks of new and re-emerging infectious diseases. This requires a better understanding and prediction of

27 May 2024

Workshop

Online
Online
Germany

public

Basic statistics with R

25 Oct 2023

Workshop

Online
Germany

public

Basic statistics with R

May 2022

Fungal Biol Rev

Intragenomic variation in nuclear ribosomal markers and its implication in species delimitation, identification and barcoding in fungi

Autoren

Paloi S et al.

Targeted test for antibiotic resistance in clinical Enterobacter species

Bacteria of the genus Enterobacter are among the most dangerous bacteria associated with hospital infections worldwide. Some of their representatives are highly resistant to commonly used antibiotics

Aug 2017

Int J Antimicrob Agents

Geographical variation in therapy for bloodstream infections due to multidrug-resistant enterobacteriaceae: a post hoc analysis of the INCREMENT study

Autoren

Harris PNA et al.

Oct 2017

Gastroenterology

Genome and Methylome Variation in Helicobacter pylori With a cag Pathogenicity Island During Early Stages of Human Infection

Autoren

Peacock SJ et al.

Jul 2022

Front Immunol

Host KIR/HLA-C Genotypes Determine HIV-Mediated Changes of the NK Cell Repertoire and Are Associated With Vpu Sequence Variations Impacting Downmodulation of HLA-C

Autoren

Vollmers S et al.

Nov 2014

Antimicrob Agents Chemother

Structural variations of the cell wall precursor lipid II and their influence on binding and activity of the lipoglycopeptide antibiotic oritavancin

Autoren

Münch D et al.