Immunodeficiency manifests in a reduced resistance to infections and, as a consequence, in an increased susceptibility to disease.
Synonyms
Immunodeficiency disease
Detailed description
Immunodeficiency can have genetic causes or manifest as a consequence of certain diseases such as HIV infections, cancer and gut diseases. It may even be induced artificially before bone marrow transplantations. The weakened immune system makes patients more susceptible to usually harmless pathogens. Persons suffering from immunodeficiencies profit a lot from vaccines and immunotherapies.
The antibiotic Bedaquiline (BDQ) was approved in 2014 specifically for the treatment of multidrug-resistant (MDR) tuberculosis (TB) and has since been an important component of successful MDR TB
Patients can participate in medical research as active partners. Researchers should consider their needs and their unique expertise in the research process, as it is a valuable resource. The Health
Prof. Ernst's working group operates at the interface of molecular microbiology, genomics, epidemiology and chemical biology to identify, investigate, and target unrecognized pathways in persistent and multidrug-resistant infections. To this end, the group conducts mechanistic investigations ...
According to the World Health Organisation (WHO), approximately 1.5 million people die each year from tuberculosis (TB), a disease of the lungs caused by Mycobacterium tuberculosis. People with a
The COVID-19 pandemic has dramatically demonstrated that the development of effective agents against viral pathogens is of great importance for global health. Although effective vaccines are available
This is what ideal medicine would look like: Doctors could specifically alter molecular processes in diseased cells in the body and thus causally cure patients. This is the goal of the German Centers
The human immunodeficiency virus HIV-1 is able to infect various tissues in humans. Once inside the cells, the virus integrates its genome into the cellular genome and establishes persistent
Workshop
Technische Universität München Einsteinstraße 25 81675München Germany
