Immunodeficiency manifests in a reduced resistance to infections and, as a consequence, in an increased susceptibility to disease.
Synonyms
Immunodeficiency disease
Detailed description
Immunodeficiency can have genetic causes or manifest as a consequence of certain diseases such as HIV infections, cancer and gut diseases. It may even be induced artificially before bone marrow transplantations. The weakened immune system makes patients more susceptible to usually harmless pathogens. Persons suffering from immunodeficiencies profit a lot from vaccines and immunotherapies.
The development of potent antiretroviral treatment (ART) strategies has significantly changed the face of the HIV/AIDS pandemic from a lethal disease to a chronic livable condition for infected individuals with access to care. However, in spite of ground-breaking advances in anti-HIV treatment, cure ...
The human immune system can effectively prevent and control viral infections. While many viruses can be neutralized and eliminated from the human body, other viruses persist after infection. However, they are often controlled throughout the entire human lifespan (e.g. certain herpes viruses like CMV ...
The further development of the vector vaccine MVA-SARS-2-S against COVID-19 by IDT Biologika GmbH and the German Center for Infection Research (DZIF) is postponed. The vector vaccine has been
Hepcludex (bulevirtide) is the first medication for the treatment of hepatitis D, a virus blocker whose development had been masterminded by DZIF Professor Dr Stephan Urban of Heidelberg University
Cologne, Marburg, Braunschweig and Ingelheim, Germany, 18 December 2020 – Cologne University Hospital (UKK), University of Marburg (UMR), the German Center for Infection Research (DZIF) and Boehringer
The Munich DZIF team led by Prof. Ulrike Protzer is developing a novel therapeutic approach to cure chronic hepatitis B. Researchers at Helmholtz Munich and Technical University of Munich (TUM) found
This year, the German Center for Infection Research (DZIF) is honouring two researchers who have been engaged in virus research for many years and are currently actively working on a vaccine against
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As part of the research activities within the German Center for Infection Research (DZIF), scientists of the Paul-Ehrlich-Institut studied specific vaccine candidates against COVID-19. They are based
