Resistome | German Center for Infection Research

Short description

The resistome refers to the totality of genes in a specific habitat or microbial community that can confer antibiotic resistance.

Detailed description

One example is the resistome of the human gut. It comprises the various resistance genes present in the microorganisms found there. Some of these genes can be transferred between bacteria and thereby contribute to the spread of antibiotic resistance.

The composition of the resistome can change over time. In particular, the use of antibiotics can give bacteria with certain resistance genes a survival advantage, thereby promoting their spread. Studying the resistome helps researchers better understand the emergence and spread of antibiotic resistance.

University Hospital Tübingen

TIARA-IMPACT: Immunological and microbiome-based predictors of postoperative infections

Postoperative infections following major abdominal surgery remain common and difficult to predict. A key reason is the incomplete understanding of how individual differences in the gut microbiome, host immunity, and microbial metabolites shape infection susceptibility. Following completion of ...

Jul 2025

Antibiotics (Basel)

Resistome and Phylogenomics of Escherichia coli Strains Obtained from Diverse Sources in Jimma, Ethiopia

Autoren

Gashaw M et al.

University of Cologne

R-Net: Core network for the study of multidrug-resistant bacterial organisms

Implementation of evidence-based infection control practices to reduce healthcare-associated infection remains a national and international priority. R-Net investigates the effect of various interventions aimed at limiting the spread of infections due to multi-drug resistant organisms (MDRO) ...

Sep 2019

BMC Biol

Distinct impact of antibiotics on the gut microbiome and resistome: a longitudinal multicenter cohort study

Autoren

Willmann M et al.

Aug 2019

Front Microbiol

Clinical Resistome Screening of 1,110 Escherichia coli Isolates Efficiently Recovers Diagnostically Relevant Antibiotic Resistance Biomarkers and Potential Novel Resistance Mechanisms

Autoren

Volz C et al.