Animal model | German Center for Infection Research

Short description

An animal model is a non-human animal species used in biomedical research because it can mimic aspects of a biological process or disease that occur in humans.

Apr 2014

Sci Transl Med

An Orally Available, Small-Molecule Polymerase Inhibitor Shows Efficacy Against a Lethal Morbillivirus Infection in a Large Animal Model

Autoren

Krumm SA et al.

Hepatitis B: Unusual virus discovered in shrews

The discovery of an unusual hepatitis B virus from shrews offers new opportunities of better understanding the chronic progression of the disease. International research teams were able to demonstrate

Gut Microbe helps thwart Salmonella

Salmonella infections can have serious consequences for certain high-risk groups, such as young children, the elderly and individuals whose immune systems are functionally compromised. Most people

Developing Medication

Developing a new medication usually takes more than ten years. Out of the several thousand substances investigated in basic and pre-clinical research, only one or two candidates are approved by

Hamburg - Lübeck - Borstel - Riems | München

MycoDrugs and Trials

The working group runs a platform to evaluate the efficacy of new drugs and to select optimal treatment options for tuberculosis patients. In vitro test systems are available for preclinical testing, which are used to test the activity of substances against tuberculosis-causing mycobacteria. An ...

Hamburg - Lübeck - Borstel - Riems

Clinical management, epidemiology and immunology of newly emerging infections

This research group, led by Professor Marylyn Addo, initiates and coordinates translational research in the field of emerging infections with a particular focus on Ebola, MERS, Lassa and Crimean-Congo haemorrhagic fever. Immunology studies, vaccine development, testing of novel anti-infectives and ...

Hannover - Braunschweig

Primary human liver cells

Primary human liver cells are required in order to investigate infections of the liver and to conduct preclinical tests of new agents. Isolating them from patient samples is a technologically challenging process requiring the highest levels of skill. This skill is available at the “Primary Human ...

Rybniker Lab at the University Hospital Cologne

Tuberculosis: Inhibiting host cell death with immunotherapy

Tuberculosis treatment still entails the intake several antibiotics over a period of many months and is torturous for many patients. The pathogen’s increasing multidrug resistance additionally

Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Preclinical development of Amidochelocardins

The challenge of antibiotic drug development today is the discovery and optimisation of novel bioactive compounds that do not show cross-resistances with clinically applied antibiotics, ideally due to a novel mode of action (MoA) which adresses unexploited microbial targets. In the case of ...

Two tick species sharing a leave: Ixodes ricinus in the front. (Please use this picture only in connection to the press release).

Scientists warn: 2018 will be the ‘year of the tick’

This summer there will be a particularly large amount of ticks and thus a higher risk of getting meningitis or Lyme disease (borreliosis), because these diseases are transmitted by ticks. Scientists