Animal model | German Center for Infection Research

Short description

An animal model is a non-human animal species used in biomedical research because it can mimic aspects of a biological process or disease that occur in humans.

Feb 2023

Nat Commun

Efficacy of an unmodified bivalent mRNA vaccine against SARS-CoV-2 variants in female small animal models

Autoren

Corleis B et al.

Jan 2023

Viruses

Animal Model Alternatives in Filovirus and Bornavirus Research

Autoren

Widerspick L et al.

Electron micrograph of a cluster of rod-shaped bacterial cells in gray.

New drug candidate found against persistent intestinal pathogens

Infections with the bacterium Clostridioides difficile (C. difficile for short) frequently recur due to permanent stages remaining in the intestine. A drug that also effectively combats the permanent

DZIF-project-derived start-up “EBViously“ announces first details of its EBV vaccine candidate

EBViously, a spin-off from Helmholtz Munich (HMGU), is led by world-leading experts in Epstein-Barr virus biology, genetics, and immunity and was founded to develop a safe and highly effective

Preparing for the next pandemic: Targeted computer modelling to accelerate antiviral drug development

Effective drugs against viral diseases like COVID-19 are urgently needed now and in the future. The emergence of viral mutants and yet unknown viruses could push vaccines to their limits. The DZIF

Apr 2022

Viruses

Henipavirus Immune Evasion and Pathogenesis Mechanisms: Lessons Learnt from Natural Infection and Animal Models

Autoren

Lawrence P

Escudero-Pérez B

Newborn baby wearing only a diaper lying face-down on the skin of a person

Exposure to antibiotics during birth by caesarean section may increase infants’ long-term health risks

Animal studies indicate that prenatal contact with antibiotics can affect the early development of intestinal flora and lead to serious long-term health problems in offspring. In a pilot study

Dec 2021

Viruses

The Bank Vole (Clethrionomys glareolus)-Small Animal Model for Hepacivirus Infection

Autoren

Röhrs S et al.

Characterisation of broadly neutralising antibodies against the hepatitis C virus

Despite improved methods of treatment, an infection with the hepatitis C virus still leads to approximately 400,000 deaths worldwide each year. The development of a vaccine is urgently required, but

Mar 2014

Antiviral Res

Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model

Autoren

Oestereich L et al.