Assay | German Center for Infection Research

Short description

Assays are standardized test systems used in laboratory medicine and pharmaceutical research to detect certain substances.

Synonyms

Assays

Detailed description

Assays are usually based on molecular biological methods. They can be qualitative or quantitative. Qualitative assays allow statements to be made as to whether or not a certain substance is present in the material under investigation. With quantitative test systems the amount can be determined. Examples of assays used in infection research and diagnostics are ELISA (Enzyme-Linked Immuno Sorbent Assay), FIA (Fluorescence Immunoassay) or PCR (Polymerase Chain Reaction).

Oct 2023

Pharmaceutics

A Single-Run HPLC–MS Multiplex Assay for Therapeutic Drug Monitoring of Relevant First- and Second-Line Antibiotics in the Treatment of Drug-Resistant Tuberculosis

Autoren

Köhler N et al.

Oct 2023

BMC Infect Dis

Species identification and drug susceptibility testing of non-tuberculous mycobacteria by Line Probe Assay in Lambaréné, Gabon-a cross-sectional study

Autoren

Ndanga MED et al.

Oct 2023

Ann Lab Med

Head-to-Head Comparison of Nine Assays for the Detection of Anti-Echinococcus Antibodies: A Retrospective Evaluation

Autoren

Mattwich C et al.

Oct 2023

Clin Microbiol Infect

A multiserological line assay to potentially discriminate current from past Helicobacter pylori infection

Autoren

Li ZX et al.

Sep 2023

Virol J

Studying temporal titre evolution of commercial SARS-CoV-2 assays reveals significant shortcomings of using BAU standardization for comparison

Autoren

Kroidl I et al.

Research Center Borstel Leibniz Lung Center

Researching lung damage, immunology, and treatment needs as sub-studies in the household cohort study ERASE-TB

With ten million cases and 1.4 million deaths in 2021 alone, Mycobacterium tuberculosis remains one of the world's most dangerous pathogens. Early diagnosis of the disease and tracking of people at increased risk of developing TB are critical to minimising infection and containing TB. The ongoing ...

A lab technician pipettes a sample into a sequencing device.

When (new) drugs don’t work: Mozambique faces alarming multidrug-resistant tuberculosis epidemic

With one of the highest tuberculosis (TB) incidences (368 cases/100,000 population) in the African region, Mozambique is particularly affected by the TB epidemic. Drug-resistant TB is also a major

Jul 2023

Chembiochem

Establishment of an In Bacterio Assay for the Assessment of Carbon Storage Regulator A (CsrA) Inhibitors

Autoren

Wu Y et al.

Aug 2023

Hepatology

HDV RNA Assays: Performance characteristics, clinical utility and challenges

Autoren

Wedemeyer H et al.

Aug 2023

Med Microbiol Immunol

Automated antigen assays display a high heterogeneity for the detection of SARS-CoV-2 variants of concern, including several Omicron sublineages

Autoren

Osterman A et al.