CD4 T lymphocyte | German Center for Infection Research

Short description

CD4 T lymphocytes form a subgroup of T lymphocytes that is responsible for cell-mediated immune responses.

Synonyms

T helper cell

CD4 cells

Detailed description

T lymphocytes carrying the surface CD4 are called T helper cells. After activation, they release substances that are either involved in cell-mediated immunity or that stimulate B cell immune responses. infects mainly this T subgroup.

Stephan Urban receives the Baruch S. Blumberg Prize 2023

Stephan Urban, DZIF professor at Heidelberg University Hospital, receives the Baruch S. Blumberg Prize 2023 from the Hepatitis B Foundation, a global non-profit organisation. The virologist is being

Jul 2022

Front Immunol

Increased Expression of Multiple Co-Inhibitory Molecules on Malaria-Induced CD8(+) T Cells Are Associated With Increased Function Instead of Exhaustion

Autoren

Brandi J et al.

Jul 2022

Proc Natl Acad Sci USA

EBNA2-EBF1 complexes promote MYC expression and metabolic processes driving S-phase progression of Epstein-Barr virus-infected B cells

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Beer S et al.

Jul 2022

J Virol

Persistent Maintenance of Intermediate Memory B Cells Following SARS-CoV-2 Infection and Vaccination Recall Response

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Pušnik J et al.

Jul 2022

Front Immunol

Review: Sustainable Clinical Development of CAR-T Cells - Switching From Viral Transduction Towards CRISPR-Cas Gene Editing

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Wagner DL et al.

Jul 2022

Methods Mol Biol

Enhanced Transduction of P2X7-Expressing Cells with Recombinant rAAV Vectors

Autoren

Mann AM et al.

May 2022

J Clin Invest

Bitter taste signaling in tracheal epithelial brush cells elicits innate immune responses to bacterial infection

Autoren

Hollenhorst MI et al.

Negative-stained transmission electron micrograph in black and white of round hepatitis B virus particles in white, in which internal structures are visible, against a dark background.

New study shows significant antiviral activity of the agent bulevirtide for the treatment of chronic hepatitis D virus infection

Between 10 and 20 million people worldwide are infected with hepatitis D virus (HDV). HDV infection is always associated with hepatitis B virus infection. So far there has been no satisfactory

Jun 2022

BMC Med

Helminth antigens differentially modulate the activation of CD4(+) and CD8(+) T lymphocytes of convalescent COVID-19 patients in vitro

Autoren

Adjobimey T et al.

Jun 2022

EMBO Rep

Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cells

Autoren

Höfle J et al.