CD4 T lymphocytes form a subgroup of T lymphocytes that is responsible for cell-mediated immune responses.
Synonyms
T helper cell
CD4 cells
Detailed description
T lymphocytes carrying the surface antigen CD4 are called T helper cells. After activation, they release substances that are either involved in cell-mediated immunity or that stimulate B cell immune responses. HIV infects mainly this T lymphocyte subgroup.
Around 260 million people, more than three percent of the global population, are chronically infected with the hepatitis B virus (HBV); in the long term, this often leads to complications such as
The development of potent antiretroviral treatment (ART) strategies has significantly changed the face of the HIV/AIDS pandemic from a lethal disease to a chronic livable condition for infected individuals with access to care. However, in spite of ground-breaking advances in anti-HIV treatment, cure ...
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Patients have a high risk of serious infections after organ or stem cell transplantation. The number of these complications is large, but too little is currently known about the links between
The human immune system can effectively prevent and control viral infections. While many viruses can be neutralized and eliminated from the human body, other viruses persist after infection. However, they are often controlled throughout the entire human lifespan (e.g. certain herpes viruses like CMV ...
The Munich DZIF team led by Prof. Ulrike Protzer is developing a novel therapeutic approach to cure chronic hepatitis B. Researchers at Helmholtz Munich and Technical University of Munich (TUM) found
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As part of the research activities within the German Center for Infection Research (DZIF), scientists of the Paul-Ehrlich-Institut studied specific vaccine candidates against COVID-19. They are based
