Dysbiosis | German Center for Infection Research

Short description

Dysbiosis refers to an unfavorable change in the composition or function of the microbiome that may be associated with health problems.

Synonyms

dysbiotic

Detailed description

Dysbiosis refers to changes in a microbial community in which, for example, the composition, diversity, or function of the microbiome is altered. Such changes can occur in the gut, on the skin, or in the mouth, among other places. Dysbiosis is associated with various diseases, including infections as well as inflammatory and immune-mediated diseases. However, it is not always clear whether the changes in the microbiome are the cause or the consequence of a disease. The term "eubiosis" is used as the opposite of dysbiosis.

Aug 2024

NPJ Biofilms Microbiomes

Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in COVID-19

Autoren

Essex M et al.

Helmholtz Centre for Infection Research

Uncovering the interplay between gut microbiota and the immune system in cirrhotic patients (TIPINF)

Bacterial infections are one of the most severe complications in patients with decompensated liver cirrhosis. The immune system of this patient group is weakened due to a complex dysfunction of the immune system (cirrhosis-associated immune dysfunction, CAID). The cause of the immune system ...

Jan 2024

Ann Surg

Microbiome Dysbiosis with Enterococcus Presence in the Upper Gastrointestinal Tract is A Risk Factor for Mortality in Patients Undergoing Surgery for Pancreatic Cancer

Autoren

Stein-Thoeringer CK et al.

Bonn - Köln

Pathogenic ecophysiology

The working group "Pathogenic ecophysiology" investigates the adaptations of resistant, enteropathogenic bacteria (such as vancomycin-resistant enterococci) to the conditions inside the human gut microbiome. The researchers analyze how interactions between bacteria and the host, as well as the shift ...

Jul 2016

J Neurosci