The hepatitis B virus (HBV) is a coated DNA virus that causes hepatitis B infection.
Synonyms
Hepatitis B virus
Detailed description
Hepatitis B is the most common chronic viral infection worldwide. The virus exists in blood and other body fluids. It infects human liver cells and propagates in them.
Developing a new medication usually takes more than ten years. Out of the several thousand substances investigated in basic and pre-clinical research, only one or two candidates are approved by
The largest trial on the treatment of aggressive hepatitis D (delta) worldwide was conducted at the German Liver Foundation’s HepNet Study House. It shows that an extension of treatment duration has
A detailed understanding of cellular immune responses in acute and chronic hepatitis is essential for the development of new drugs against hepatitis B and D infections. This means that standardized immunomonitoring under the necessary security conditions of risk level 3 is required, where immune ...
A microscopy unit was established at the Heidelberg Partner Site for research groups from the research field “Hepatitis” and other research fields including “Emerging Infections”, “Malaria and Neglected Tropical Diseases” and “HIV” in particular. The working group microscopy of hepatitis viruses ...
In addition to analyzing the replication mechanisms of the hepatitis B (HBV) and D (HDV) viruses, the work of Prof. Stephan Urban and his team focuses on the development of new active substances and drugs against these pathogens. With Bulevirtide (formerly Myrcludex B), which blocks the binding and ...
The HepNet Study-House connects individual study centers in the field of hepatitis research and creates a central platform to conduct clinical studies (Investigator Initiated Trials) and build patient cohorts in the field of viral hepatitis. On the one hand, the Study-House is a contact point for ...
United against infections The corona pandemic has made it clear how important infection research is. However, the emergence and spread of unknown viruses such as, most recently, SARS-CoV-2 is not new