Hospital pathogens are microorganisms that patients can get infected with in connection with hospital treatment.
The most common hospital pathogens are enterococci, Pseudomonas aeruginosa and staphylococci. Inadequate hygiene measures and incorrectly applied antibiotics are two reasons for their spread. The increase of hospital pathogens carrying antibiotic resistances is particularly alarming. Hospital-acquired infections can lead to wound infections and sepsis as well as infections of the airways and the urinary tract.
In this project, the scientists develop genetically engineered phage lysins and specific bacteriocins for the elimination of hospital germs such as Staphylococcus aureus, they clarify mechanisms of potential resistance mechanisms, and they analyse whether broad-spectrum or specifically acting agents ...
The clinical research unit led by Prof. Evelina Tacconelli combines the information from clinical, microbiological and basic research. Scientists and physicians are working closely together to tackle the problem of increasing antibiotic-resistant germs in hospitals. Samples are collected in clinical ...