Multidrug resistance | German Center for Infection Research

Short description

Multidrug resistance means that bacteria or viruses are insensitive towards various antibiotics or antivirals, respectively.

Synonyms

Multiple drug resistance

Detailed description

There is a general increase of resistances against antibiotics. Infections with multidrug-resistant pathogens pose a serious problem as their treatment with antibiotics is difficult or not possible any more.

Dec 2017

Respir Med

Infection control, genetic assessment of drug resistance and drug susceptibility testing in the current management of multidrug/extensively-resistant tuberculosis (M/XDR-TB) in Europe: A tuberculosis network European Trialsgroup (TBNET) study

Autoren

Bothamley GH

Lange C

Aug 2022

Genome Med

High fluoroquinolone resistance proportions among multidrug-resistant tuberculosis driven by dominant L2 Mycobacterium tuberculosis clones in the Mumbai Metropolitan Region

Autoren

Dreyer V et al.

Aug 2022

PLoS One

Prediction of drug resistance by Sanger sequencing of Mycobacterium tuberculosis complex strains isolated from multidrug resistant tuberculosis suspect patients in Ethiopia

Autoren

Mesfin EA et al.

Prof Dirk Heinz, Prof Dirk Busch and Bettina Stark-Watzinger focus on a presentation

Federal Research Minister learns about current infection research at the HZI and DZIF

As part of her autumn tour, the Federal Minister of Education and Research, Bettina Stark-Watzinger, visited the Helmholtz Centre for Infection Research (HZI) and the German Center for Infection

Left panel: grey electron microscopic image of rod-shaped M. tuberculosis bacteria; right panel: image of a circular phylogenetic tree depicting the genetic relationship between M. tuberculose strains

Personalised antibiotic treatment strategies for tuberculosis patients

Tuberculosis is one of the leading causes of death worldwide, with an estimated 1.4 million deaths and ten million people infected annually. Resistant and multidrug-resistant (MDR) variants of the

Apr 2022

JAC Antimicrob Resist

Whole genome sequencing-based drug resistance predictions of multidrug-resistant Mycobacterium tuberculosis isolates from Tanzania

Autoren

Mbelele PM et al.

Mar 2022

Comput Struct Biotechnol J

Multi-label classification for multi-drug resistance prediction of Escherichia coli

Autoren

Ren Y et al.

Visualisation of luminous strands of DNA as well as of a ring that depicts the combined analysis of many different bacterial genomes.

Only three percent of potential bacterial drug sources known

The emergence of antibiotic-resistant pathogens and the increasing difficulty in developing new drugs has contributed to global challenges in combating infectious diseases. An extensive bioinformatics

Feb 2022

Malar J

Challenges in the clinical development pathway for triple and multiple drug combinations in the treatment of uncomplicated falciparum malaria

Autoren

Bassat Q et al.

World Tuberculosis Day 2022: Saving lives

"Invest to end TB. Save Lives" is the theme of this year's World Tuberculosis Day, which annually on 24 March commemorates the relevance and worldwide spread of this deadly infectious disease. As an