Multidrug resistance means that bacteria or viruses are insensitive towards various antibiotics or antivirals, respectively.
Synonyms
Multiple drug resistance
Detailed description
There is a general increase of resistances against antibiotics. Infections with multidrug-resistant pathogens pose a serious problem as their treatment with antibiotics is difficult or not possible any more.
The Cologne-based research project "INNOPAK", which focuses on developing innovative precision antibodies against infections with antibiotic-resistant Pseudomonas aeruginosa-bacteria, will receive
Pseudomonas aeruginosa is a multidrug-resistant bacterium that can cause life-threatening infections, such as sepsis and pneumonia. One of the key weapons used by this bacterium is the type III secretion system (T3SS), which contains the protein PcrV. Researchers at the DZIF discovered that patients ...
The human gut is home to a dense network of microorganisms, collectively known as the gut microbiome, which actively contributes to health. These microorganisms aid digestion, train the immune system
If an intestinal inhabitant such as the bacterium Escherichia coli (E. coli) becomes resistant to many antibiotics, it can cause serious health problems if it enters the bloodstream. How can such
The German Research Foundation (DFG) and the French Agence National de la Recherche (ANR) are now funding the project "Characterization of novel natural product binding sites in the DNA gyrase of
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Pathogenic strains of Salmonella inject effector proteins into the cells of the gastrointestinal tract to invade and multiply within them. The bacteria are usually ingested with contaminated food
Gram-negative bacteria are naturally insensitive to many antibiotics due to their additional outer membrane. In addition, the bacteria have acquired resistance to clinically used antibiotics in recent decades, resulting in multidrug-resistant bacteria. Novel classes of antibiotics are needed to ...
Antimicrobial resistance (AMR) is one of the most urgent challenges facing global health and development. Described as a “creeping pandemic” by the G7 forum of leading economic nations, AMR occurs
The novel active agent HY-133, which was developed by HYpharm and prepared for clinical trials in collaboration with the German Center for Infection Research (DZIF) and universities in Tübingen
