Multidrug resistance means that bacteria or viruses are insensitive towards various antibiotics or antivirals, respectively.
Synonyms
Multiple drug resistance
Detailed description
There is a general increase of resistances against antibiotics. Infections with multidrug-resistant pathogens pose a serious problem as their treatment with antibiotics is difficult or not possible any more.
Gram-negative bacteria are naturally insensitive to many antibiotics due to their additional outer membrane. In addition, the bacteria have acquired resistance to clinically used antibiotics in recent decades, resulting in multidrug-resistant bacteria. Novel classes of antibiotics are needed to ...
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The novel active agent HY-133, which was developed by HYpharm and prepared for clinical trials in collaboration with the German Center for Infection Research (DZIF) and universities in Tübingen
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Proteins form different conformations in combination with other proteins—as multimers or heterocomplexes—than when they are present as monomers. Static descriptions of protein structures are therefore often not sufficient to describe their dynamic properties. Nevertheless, current simulations of ...
Antibiotic resistance is one of the challenges facing mankind in the 21st century. This includes antibiotic-resistant tuberculosis. Just in time for World Tuberculosis Day on 24 March 2024, the
While tuberculosis (TB) has become relatively rare in Germany and other industrialised nations, around ten million people contract the bacterial infection every year, especially in resource-poorer
A recent clinical study shows that ganfeborole could be a promising candidate for the safe and effective treatment of pulmonary tuberculosis. Using microbiological testing and innovative imaging