Rifampicin | German Center for Infection Research

Short description

Rifampicin is an antibiotic especially used to treat mycobacterial infections.

Detailed description

Rifampicin inhibits the RNA polymerase – a bacterial enzyme needed for protein production.

Sep 2021

BMC Infect Dis

Transmission patterns of rifampicin resistant Mycobacterium tuberculosis complex strains in Cameroon: a genomic epidemiological study

Autoren

Merker M et al.

Mar 2021

Antimicrob Agents Chemother

Thin layer agar-based direct phenotypic drug-susceptibility testing on sputum in Eswatini rapidly detects Mycobacterium tuberculosis growth and rifampicin resistance, otherwise missed by WHO endorsed diagnostic tests

Autoren

Ardizzoni E et al.

Feb 2021

Eur Respir J

Increased bactericidal activity but dose-limiting intolerability at 50 mg·kg(-1) rifampicin

Autoren

Te Brake LHM et al.

Tailor-made therapy of multi-resistant tuberculosis

The successful treatment of multidrug-resistant tuberculosis requires clarification in advance as to which antibiotics the pathogens are resistant to. Classic testing in the laboratory is very time

Dec 2020

Int J Tuberc Lung Dis

Systematic rifampicin resistance errors with Xpert(®) MTB/RIF Ultra: implications for regulation of genotypic assays

Autoren

Omar SV et al.

Nov 2020

Proc Natl Acad Sci U S A

The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase

Autoren

Lilic M et al.

Undetected and difficult to treat: multidrug resistant tuberculosis strain

Scientists at the Research Center Borstel and the German Center for Infection Research (DZIF) identified a multidrug resistant Tuberculosis-strain in Southern Africa, that is not detected by modern

May 2020

J Antimicrob Chemother

Combination therapy with rifampicin or fosfomycin in patients with Staphylococcus aureus bloodstream infection at high risk for complications or relapse: results of a large prospective observational cohort

Autoren

Rieg S et al.

May 2019

Pneumologie

Joint Statement on the New WHO Recommendations for Treatment of Multidrug- and Rifampicin-Resistant Tuberculosis

Autoren

Maurer FP et al.

Nov 2018

Antimicrob Agents Chemother

A diagnostic algorithm to investigate pyrazinamide and ethambutol resistance in rifampicin resistant Mycobacterium tuberculosis isolates in a low incidence setting

Autoren

Andres S et al.