Pseudomonas aeruginosa is a multidrug-resistant bacterium that can cause life-threatening infections, such as sepsis and pneumonia. One of the key weapons used by this bacterium is the type III secretion system (T3SS), which contains the protein PcrV. Researchers at the DZIF discovered that patients with chronic infections develop highly effective [...]

The prospective, multicenter study, "mEX-TB," aims to improve care for patients with extrapulmonary tuberculosis (EPTB). To this end, the study will identify biomarkers to detect risk factors for developing EPTB and enable biomarker-based diagnosis and treatment of patients in the future. To achieve this, clinical data and biosamples from EPTB [...]