Eine Kamera ist auf eine reflektierende Glasscheibe gerichtet.
© DZIF

News

All current DZIF news can be found here.

The pathogen Clostridioides difficile
© CDC/Medical Illustrator: Jennifer Oosthuizen

Well-Known Natural Compound Shows Unexpected Effect Against a Dreaded Pathogen

Treatment with broad-spectrum antibiotics often leads to side effects, as it affects not only the pathogens but also the “good” bacteria in the gut. A research team from Hannover Medical School (MHH)

A gloved hand holds a vaccine vial labeled “Ervebo_solution for injection_rVSVΔG-ZEBOV-GP_live_1 dose”
© Deutsches Museum/Alexander Goettert

Ebola vaccine induces T cell cross-reactivity against Bundibugyo virus in humans

The ongoing Bundibugyo ebolavirus (BDBV) outbreak in the Democratic Republic of the Congo is the second-largest Ebolavirus outbreak globally, with more than 6,000 confirmed cases and a mortality rate

The PhalconBio logo appears on a blue background featuring silhouettes of people.
© INCATE

INCATE awards PhalconBio Stage II Funding to advance Dual-Action Phages for severe bacterial pneumonia

The Incubator for Antimicrobial Therapies in Europe, INCATE, aims to support innovators in the early stages of developing therapies in the field of antimicrobial resistance. The German Center for

Electron micrograph of Segatella copri (strain HDD04).
© HZI/Mathias Müsken

Dietary fiber does not act alone in the microbiome

Why do the gut microbiomes of people from industrialized and non-industrialized regions differ? A study by the research team led by DZIF scientist Prof. Till Strowig of the Helmholtz Centre for

AI-generated image of a DNA helix accompanied by glowing lines and a background of stylized microorganisms
© HZI; KI-generiert

A clearer picture of microbial communities: Metax improves taxonomic profiling

In acute, life-threatening infections, rapidly characterizing the microorganisms in a patient sample can help guide diagnosis and treatment. This is possible by using computational methods known as

Molecular structures of corramycin and DNA gyrase, with a graphic illustration showing where corramycin binds to the gyrase
© HIPS/Fries

A new mechanism of action against an old enemy

According to the World Health Organization (WHO), tuberculosis (TB) affects more than 10 million people and causes over a million deaths each year, making it one of the world’s deadliest infectious

Agar plates with visible phage plaques.
© AG Würstle/Universitätsmedizin Frankfurt

Common standards for the use of phages against hard-to-treat infections

An international working group led by the German Society for Infectious Diseases (DGI) has developed a guideline for personalized phage therapy. Twenty professional organizations, 18 international

Filamentous virus particle
© CDC/Frederick A. Murphy

Faster diagnostics, deeper insights: Researchers strengthen response to Ebola outbreaks

The current outbreak of Bundibugyo virus (BDBV) in the Democratic Republic of the Congo highlights the challenges of responding to rare but potentially devastating infectious diseases. Two studies led

Scientist working with an automated bioreactor system in a biotechnology laboratory.
© Celonic AG

PANTIPA project: Antibody against Pseudomonas aeruginosa reaches next development phase

The DZIF flagship project PANTIPA has reached an important milestone. Following successful preclinical work at the University Hospital Cologne and the Helmholtz Centre for Infection Research, the

First authors of the study Dr. Metodi Stankov (left) and Dr. Matthias Bruhn at TWINCORE.
© TWINCORE/Grabowski

Booster vaccination strengthens existing defenses

The SARS-CoV-2 virus is constantly mutating. As a result, vaccines become less effective and require regular adaptation. This was the case in 2025 with the JN.1 variant. An interdisciplinary team from