Antigen | German Center for Infection Research

Short description

An antigen is a foreign substance that elicits a specific immune response, or that itself is the target of such an immune response.

Detailed description

Antigens are generally foreign substances. They are recognized by antibodies and certain receptors on immune cells. Proteins, carbohydrates, and lipids can function as an antigen.

Dec 2024

J Biol Chem

A fucose-binding superlectin from Enterobacter cloacae with high Lewis and ABO blood group antigen specificity

Autoren

Beshr G et al.

Dec 2024

Tuberculosis (Edinb)

Blood levels of Mycobacterium tuberculosis (Mtb)antigen-triggered immune markers in people exposed to tuberculosis with regard to Mtb infection status and receipt of tuberculosis preventive therapy

Autoren

Holmberg P et al.

Dec 2024

Nat Commun

High-resolution profile of neoantigen-specific TCR activation links moderate stimulation to increased resilience of engineered TCR-T cells

Autoren

Füchsl F et al.

Dec 2024

Int J Mol Sci

Longitudinal Study of SARS-CoV-2 Vaccinations and Infections in Patients with Gastrointestinal Cancer: Stabilizing Immune Responses and Neutralizing Emerging Variants with Variant-Adapted Antigen Exposures

Autoren

Gonzalez-Carmona MA et al.

Dec 2024

Viruses

A Global Collaborative Comparison of SARS-CoV-2 Antigenicity Across 15 Laboratories

Autoren

Brangel P et al.

Oct 2024

Parasitol Res

Differences of in vitro immune responses between patent and pre-patent Litomosoides sigmodontis-infected mice are independent of the filarial antigenic stimulus used

Autoren

Arndts K et al.

Oct 2024

Int J Mol Sci

Implementation of an Immunoassay Based on the MVA-T7pol-Expression System for Rapid Identification of Immunogenic SARS-CoV-2 Antigens: A Proof-of-Concept Study

Autoren

Kumar S et al.

Oct 2024

NPJ Vaccines

A multiantigenic Orf virus-based vaccine efficiently protects hamsters and nonhuman primates against SARS-CoV-2

Autoren

Reguzova A et al.

Sep 2024

J Infect Dis

Ebola Virus Infection of Flt3-Dependent, Conventional Dendritic Cells and Antigen Cross-presentation Leads to High Levels of T-Cell Activation

Autoren

Niemetz L et al.

Heidelberg University Hospital

Mechanisms of host infection control in immunosuppressed and infection-prone individuals

Organ transplant patients usually have to take immunosuppressive drugs for the rest of their lives to prevent their bodies from rejecting the organs. This therapy suppresses the physiological immune response to tumors and infections. The therapeutic goal for this patient group is to achieve an ...