Filarial worms are nematodes, which are parasites and can cause disease in humans.
Synonyms
Filariae
Detailed description
Filarial worms are transmitted by mosquitoes from one person to another. Besides, important steps in their life cycle take place in the mosquito. In humans, they cause so-called filariasis, which mainly affects the lymphatic vessels.
Prof. Marc Hübner aims to identify new drug candidates against parasitic threadworms, so-called filariae, and developing them further for human use. To this end, new in vitro and in vivo models are being developed and identified candidates are being tested in clinical trials in humans. With ...
Worms and other parasites cause numerous and widespread tropical diseases which are largely overlooked. At the DZIF, research teams are focused on fighting these diseases. Since August 2020
More than 21 million people in Africa are infected with the threadworm Onchocerca volvulus, the pathogen causing river blindness. About one in ten of those affected goes blind. What is needed are active agents that kill the long-lived adult worms. With Corallopyronin A, DZIF scientists have found an ...
In 2009, Prof. Achim Hörauf and his team at the University Hospital Bonn discovered that the natural substance Corallopyronin A is effective against filarial worms. Infections with these worms can
Dr. Ute Klarmann-Schulz’s research group’s objective is to support the transition of new anti-infective agent candidates from preclinical into clinical phases of development, and to ensure that the first clinical trials run as smoothly as possible. In the field of preclinical development, the junior ...
Tsutsugamushi fever, or “scrub typhus”, is an infectious disease related to typhus, which is endemic in large parts of Asia. The disease has an estimated incidence of approximately one million cases
