The immune system comprises organs, tissues, cells and molecules, which protect the body against pathogens.
Detailed description
The biological defense system can be separated into an innate and an adaptive part. The innate immune system developed early in the phylogeny of living things. The adaptive immune system adjusts to new or modified pathogens. Both parts collaborate closely. Moreover, the immune system can destroy abnormal or defective cells of the own body.
Influenza vaccines need to be evaluated every year to ensure they remain effective against new influenza viruses. Will the same apply to COVID-19 vaccines? In order to gauge whether and to what extent
The project “Clinical cohorts for HIV remission” will continue and expand ongoing research around the treatment of primary HIV infection (TopHIV) Cohort of patients with acute HIV infection. Beyond studies about their immune responses and reservoir formation, selected TopHIV individuals will be ...
Marc Hübner aims to identify new drug candidates against parasitic threadworms, so-called filariae, and developing them further for human use. To this end, new in vitro and in vivo models are being developed and identified candidates are being tested in clinical trials in humans. With oxfendazole ...
Hepatitis E is an infectious disease of the liver found across the globe. It is caused by the hepatitis E virus and in most cases heals by itself. However, in patients with a suppressed immune system
Worms and other parasites cause numerous and widespread tropical diseases which are largely overlooked. At the DZIF, research teams are focused on fighting these diseases. Since August 2020
The development of potent antiretroviral treatment (ART) strategies has significantly changed the face of the HIV/AIDS pandemic from a lethal disease to a chronic livable condition for infected individuals with access to care. However, in spite of ground-breaking advances in anti-HIV treatment, cure ...
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Patients have a high risk of serious infections after organ or stem cell transplantation. The number of these complications is large, but too little is currently known about the links between
The human immune system can effectively prevent and control viral infections. While many viruses can be neutralized and eliminated from the human body, other viruses persist after infection. However, they are often controlled throughout the entire human lifespan (e.g. certain herpes viruses like CMV ...
The Munich DZIF team led by Prof. Ulrike Protzer is developing a novel therapeutic approach to cure chronic hepatitis B. Researchers at Helmholtz Munich and Technical University of Munich (TUM) found
