Virulence | German Center for Infection Research

Short description

Virulence is a ’s ability to cause disease. It determines the degree of pathogenicity.

Detailed description

Virulence is determined through virulence factors of the , which help the pathogen to spread within the infected host.

Sep 2021

Eur J Med Chem

Divergent synthesis and biological evaluation of 2-(trifluoromethyl)pyridines as virulence-attenuating inverse agonists targeting PqsR

Autoren

Schütz C et al.

INCATE selects first innovators to support in the fight against drug-resistant bacterial infections

With INCATE (INCubator for Antibacterial Therapies in Europe), the German Center for Infection Research (DZIF) has participated in the foundation of a European initiative to take up the fight against

Sep 2014

Front Cell Infect Microbiol

The Mycobacterium avium ssp. paratuberculosis specific mptD gene is required for maintenance of the metabolic homeostasis necessary for full virulence in mouse infections

Autoren

Meißner T et al.

Apr 2021

Elife

Common virulence gene expression in adult first-time infected malaria patients and severe cases

Autoren

Wichers JS et al.

Apr 2021

Antibiotics (Basel)

Clonal Clusters, Molecular Resistance Mechanisms and Virulence Factors of Gram-Negative Bacteria Isolated from Chronic Wounds in Ghana

Autoren

Dekker D et al.

Jan 2021

Front Microbiol

Transcriptomic Basis of Serum Resistance and Virulence Related Traits in XDR P. aeruginosa Evolved Under Antibiotic Pressure in a Morbidostat Device

Autoren

Javed M et al.

PANTIPA: Monoclonal antibodies targeting Pseudomonas aeruginosa

is a multidrug-resistant bacterium that can cause life-threatening infections, such as and pneumonia. One of the key weapons used by this bacterium is the type III

Jul 2020

Microorganisms

Comprehensive Host Cell-Based Screening Assays for Identification of Anti-Virulence Drugs Targeting Pseudomonas aeruginosa and Salmonella Typhimurium

Autoren

von Ambüren J et al.

Jul 2020

Sci Rep

Helicobacter pylori patient isolates from South Africa and Nigeria differ in virulence factor pathogenicity profile and associated gastric disease outcome

Autoren

Palamides P et al.

Apr 2020

Immunity

Chemosensory Cell-Derived Acetylcholine Drives Tracheal Mucociliary Clearance in Response to Virulence-Associated Formyl Peptides

Autoren

Perniss A et al.