The know-how for microbiome analysis coalesces at the Centre for GI Microbiome Research (CEGIMIR). The gastrointestinal microbiome, i.e. all the microorganisms in the gastrointestinal tract, plays a key role in the course of infections. Changes in composition, such as those caused by environmental factors or diseases, may, among other things, increase susceptibility to infections. A variety of modern methods is required to gain a better understanding of the microorganisms inside and their interdependencies with humans. At CEGIMIR, gene sequencing is just as important as the bioinformatic interpretation and analysis of data using various methods.
Among other things, CEGIMIR supported the SPEKTRUM study, which aims to identify components of the intestinal microbiome that influence the risk of infection with Clostridium difficile.