While there are treatment options for the immunodeficiency syndrome AIDS today, there is still not a cure. This is mainly due to the fact some of the human immunodeficiency viruses invade the genome of the host, where they cannot be attacked. Therapeutic agents can only destroy the free viruses in the blood. Once the therapy stops, the hidden viruses become active and re-enter the blood stream. Dr. Marina Lusic and her team are examining this latency. The researchers want to understand the mechanisms and use it to develop strategies for a cure. One approach is to reactivate the persistent viruses with new drugs and then target and destroy them in the blood.