München

Host-microbiome interactions

A sequencing platform will be made available as part of this research unit, whose focus is translational microbiome research. The know-how for sequencing and bioinformatic data analysis is used in various preclinical and clinical trials at the DZIF. One example is the so-called SPEKTRUM study, which ...

Bonn - Köln

Humanized Mouse Core Cologne

Humanised mice carrying human genes or cells, for example, are a crucial model for disease research and drug development. Generating them and keeping them in optimal conditions requires a lot of know-how and experience. Therefore, a professional central unit with humanised mice (Humanized Mouse Core ...

München

Immune control of viral latency and reactivation

Andreas Moosmann’s research group investigates the immune system’s responses to viruses, particularly T cell responses. Widespread viruses such as the Epstein-Barr virus and the cytomegalovirus are at the core of their interest. After infecting healthy individuals, these viruses often remain in the ...

München

Immune monitoring and cell sorting

A detailed understanding of cellular immune responses in acute and chronic hepatitis is essential for the development of new drugs against hepatitis B and D infections. This means that standardised immunomonitoring under the necessary security conditions of risk level 3 is required, where immune ...

München

Immunopathology and viral infection

Professor Andreas Pichlmair and his team study the interactions between viruses and the human immune system. They aim to determine how the immune system reacts to an external attack and how this affects the pathogen. Human cells have developed a technique to combat viruses. However, viruses ...

Hannover - Braunschweig

Infectious diseases professorship with a focus on hepatology

Professor Markus Cornberg and his translational research group provide the necessary link between hospitals, the HepNet Study House trial platform and scientific activities at the DZIF. At the Hannover Medical School, Cornberg is clinically responsible for the Hepatitis Outpatient Clinic and for the ...

München

International Clinical Trials Unit

New HIV infections occur mostly outside of Europe. That is why the DZIF has set up its own task force to coordinate clinical trials on location (mainly in Africa). The "International Clinical Trials Unit" gives DZIF member institutions access to large existing cohorts and biobanks that they can use ...

Heidelberg

Malaria: From bench to bedside

The use of insecticides has been very successful in controlling the transmission of malaria pathogens over the past decades. However, this success is threatened by the widespread and intense levels of insecticide resistance in Anopheles mosquitoes, which transmit malaria. The working group of ...

Hamburg - Lübeck - Borstel - Riems

Mathematical models and biostatistics

The research group “Mathematical models and biostatistics” supports scientists in the field of malaria research with bioinformatics methods. Their aim is to more accurately determine the courses of infection, the spread of pathogens and human immune responses. In addition, their studies provide data ...

Hannover - Braunschweig

Medical microbiome research

Guntram Graßl and his team study interactions between microbiomes and human hosts, as well as between microbiomes and bacterial pathogens in the gut. Scientists assume that certain bacteria or groups of bacteria protect the gut from pathogens by ensuring that Salmonella or Clostridioides difficile ...