A resistance gene contains the information for the production of a protein that makes an antibiotic ineffective and hence confers resistance against an antibiotic to a pathogen.
Resistance genes are usually found on a ring-shaped piece of DNA, the plasmid. Like this, they can easily be passed on from one bacterium to another. Plants can possess resistance genes as well. They are usually directed against herbicides and pests.
A large number of innovative methods are available today to specifically target bacterial pathogens: DZIF scientists in the "TARGET" project use modern sequencing technologies to classify and characterize multi-resistant gram negative pathogens on a genome-by-genome basis. Conceptually, they are ...