The University Medical Center Freiburg is a partner of several DZIF projects. The clinic works on finding out which gene mutations are responsible for chronic mucocutaneous candidiasis, a chronic infection of the skin and mucous membrane with candida fungi. Additionally, scientists are looking to find genetic factors associated with increased susceptibility to infection. They intend to identify biomarkers that permit better infection control. The clinic is working on two studies aimed at reducing hospital-associated infections. For example, antibiotics should be used more purposefully and hospital hygiene measures must be improved. A multicentric study is currently in preparation with patients facing increased risk of infection with Clostridium difficile pathogens. Freiburg is one of six sites in which the epidemiology of multidrug-resistant bacteria and the epidemiology of bloodstream infections and Clostridium difficile infections are studied longitudinally over a four-year period. Human cytomegalovirus (HCMV) infections pose a risk to immunocompromised individuals (such as AIDS or transplant patients). The researchers are looking for new drugs against HCMV.