Welcome to the DZIF -

the German Center for Infection Research

Research Areas

DZIF is doing research in nine areas:

Community-Acquired Infections at Mucosal Interfaces

Hepatitis

HIV

Infections of the Immunocompromised Host

Healthcare-Associated Infections

Malaria and Neglected Tropical Diseases

Emerging Infections

Novel Antibiotics

Tuberculosis

News

News and Press Releases:

The GUARDIAN project uses AI to combat antibiotic-resistant bacteria.
© JLU (Generated by AI using ChatGPT)

Kickoff meeting for the GUARDIAN research project in Giessen marks the launch of interdisciplinary collaboration against antibiotic resistance

Model of a hepatitis E virus particle
© RUB, Marquard

Promising active substance against hepatitis E identified

Around 70,000 people die each year from infections with the hepatitis E virus. There is currently neither a vaccine nor a specific drug against this virus. This could change with the identification of
Symbolic photo, lab work
© Vic Josh/adobe.stock.com

Innovation in Tuberculosis Treatment: New International Study Launched

The Institute of Infectious Diseases and Tropical Medicine has announced the inclusion of the first study participant in the STEP2C Stage 3 trial. The study is part of the international UNITE4TB
A man and a woman in blue surgical gowns and blue gloves are looking at a monitor. The woman is holding medical equipment in her hands. They are surrounded by other medical equipment.
© MHH/Karin Kaiser

Precision medicine for the liver

Approximately one in 10,000 people in Germany is affected by primary sclerosing cholangitis (PSC). In order to digest fats from food, the intestine needs bile. This is produced in the liver and from
Christoph Lange accepts the DZIF Prize for Translational Infection Research
© DZIF/Dirk Baumbach

Christoph Lange receives the DZIF Prize for Translational Infection Research 2025

He is one of the world's leading clinical researchers in the field of tuberculosis (TB): Prof. Dr. Dr. h. c. Christoph Lange has been awarded the DZIF Prize for Translational Infection Research 2025
All news

What is the DZIF? Find out more in our

DZIF movie

More than 700 people work at the DZIF with the common goal of translating basic research into clinical practice. The well-being of the patient is our primary focus. Get more insights in our new DZIF film:

Watch the movie
A GIF animation with clips from the DZIF film.

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Research in Focus

Hamburg - Lübeck - Borstel - Riems

Clinical Tuberculosis Center

The Clinical Tuberculosis Center provides the expertise and infrastructure for the optimization, prevention, diagnosis, and treatment of tuberculosis (TB) as well as for translating research results into clinical practice. The main objectives of the Clinical Tuberculosis Center include coordinating clinical research activities involving the DZIF TB cohort. This cohort includes [...]

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Hannover - Braunschweig | Heidelberg | München | Tübingen

Transplant Cohort

Medical data and biological samples obtained from transplant patients are collected and managed across Germany with the help of the DZIF Transplant Cohort. The data and samples form the basis of scientific studies which investigate the connections between numerous factors influencing an organ’s susceptibility to infection and organ function. By [...]

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Hannover - Braunschweig

Preclinical development of Amidochelocardins

The challenge of antibiotic drug development today is the discovery and optimisation of novel bioactive compounds that do not show cross-resistances with clinically applied antibiotics, ideally due to a novel mode of action (MoA) which adresses unexploited microbial targets. In the case of chelocardin, this antibiotic substance was identified several [...]

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Tübingen

New strategies for specific eradication of Staphylococcus aureus

In this project, the scientists develop genetically engineered phage lysins and specific bacteriocins for the elimination of hospital germs such as Staphylococcus aureus, they clarify mechanisms of potential resistance mechanisms, and they analyse whether broad-spectrum or specifically acting agents have a more effective and lasting effect on colonization by [...]

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Our Partner Sites

Location

Bonn - Köln

Research areas
Contact person
Prof Achim Hörauf: Coordinator of the consortium "Neglected tropical diseases" at DZIF.

Prof. Dr. Achim Hörauf

University Hospital Bonn
Deputy Partner Site Speaker Bonn-Köln
Deputy Coordinator Malaria and Neglected Tropical Diseases
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Location

Hannover - Braunschweig

Research areas
Contact person
Silke Hartmann

Dr. Silke Hartmann

Hannover Medical School
Partner Site Manager Hannover - Braunschweig
Project Manager Community-Acquired Infections at Mucosal Interfaces
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Location

Hamburg - Lübeck - Borstel - Riems

Research areas
Contact person
Nicole Fischer

Prof. Dr. Nicole Fischer

University Medical Center Hamburg-Eppendorf
Deputy Partner Site Speaker Hamburg-Lübeck-Borstel-Riems
Coordinator Bridging Topic "Diagnostics"
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München Tübingen Heidelberg Gießen – Marburg – Langen Bonn – Köln Hannover – Braunschweig Hamburg – Lübeck Borstel – Riems