Welcome to the DZIF -

the German Center for Infection Research

Research Areas

DZIF is doing research in nine areas:

Community-Acquired Infections at Mucosal Interfaces

Hepatitis

HIV

Infections of the Immunocompromised Host

Healthcare-Associated Infections

Malaria and Neglected Tropical Diseases

Emerging Infections

Novel Antibiotics

Tuberculosis

News

News and Press Releases:

Computer-generated image of a phage attached to the surface of a bacterial cell and injecting its DNA into the cell.
© Matthieu Louis/stock.adobe.com

Viruses against bacteria: EU funds phage therapy with €15 million

Red-coloured rod-shaped bacteria in an electron micrograph.
© CDC/Alissa Eckert; James Archer

New genomic test reveals hidden drug-resistant tuberculosis in Eswatini

Researchers in Eswatini, in collaboration with an international consortium, have made a significant breakthrough in tuberculosis (TB) diagnostics. Using targeted genome sequencing, they detected drug
Treatment of a patient during the clinical study of SPAP in Gabon
© Ghyslain Mombo-Ngoma

Promising single-dose malaria treatment advances toward pan-African clinical trial

Researchers at the German Center for Infection Research (DZIF) have developed a promising single-dose malaria treatment that could help address growing drug resistance and simplify treatment for
Members of the PKAMR and invited experts engaged in discussion
© DNAMR

Parliamentary Group against Antimicrobial Resistance (PKAMR): strengthening antibiotic innovation, ensuring access

On June 12, 2026, the Parliamentary Group against Antimicrobial Resistance (PKAMR) held a discussion under the title "High-tech agenda for antibiotics—strategic directions for innovation and security
Multicolor fluorescence microscopy image of a cell infected with Ebola viruses.
© BNITM/Lina Widerspick

Hiding in the central nervous system: using cerebral organoids to better understand Ebola virus biology

Following infection, the Ebola virus can survive unnoticed in the human body for months or even years, hiding in areas with little immune surveillance like the central nervous system. The danger is
All news

What is the DZIF? Find out more in our

DZIF video

More than 700 people work together across the DZIF with the shared goal of translating findings from basic research into clinical practice. The well-being of patients is at the center of our work.

Watch our short video to learn more
A GIF animation with clips from the DZIF film.
© DZIF

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Research in Focus

Hannover - Braunschweig | Heidelberg | München | Tübingen

Transplant Cohort

Medical data and biological samples obtained from transplant patients are collected and managed across Germany with the help of the DZIF Transplant Cohort. The data and samples form the basis of scientific studies which investigate the connections between numerous factors influencing an organ’s susceptibility to infection and organ function. By [...]

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Hamburg - Lübeck - Borstel - Riems

Clinical Tuberculosis Center (ClinTB)

The Clinical Tuberculosis Center provides the expertise and infrastructure for the optimization, prevention, diagnosis, and treatment of tuberculosis (TB) as well as for translating research results into clinical practice. The main objectives of the Clinical Tuberculosis Center include coordinating clinical research activities involving the DZIF TB cohort. This cohort includes [...]

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Tübingen

New strategies for specific eradication of Staphylococcus aureus

In this project, the scientists develop genetically engineered phage lysins and specific bacteriocins for the elimination of hospital germs such as Staphylococcus aureus, they clarify mechanisms of potential resistance mechanisms, and they analyse whether broad-spectrum or specifically acting agents have a more effective and lasting effect on colonization by [...]

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Hannover - Braunschweig

Preclinical development of Amidochelocardins

The challenge of antibiotic drug development today is the discovery and optimisation of novel bioactive compounds that do not show cross-resistances with clinically applied antibiotics, ideally due to a novel mode of action (MoA) which adresses unexploited microbial targets. In the case of chelocardin, this antibiotic substance was identified several [...]

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Our Partner Sites

Location

Hamburg - Lübeck - Borstel - Riems

Research areas
Contact person
Nicole Fischer

Prof. Dr. Nicole Fischer

University Medical Center Hamburg-Eppendorf
Deputy Partner Site Speaker Hamburg-Lübeck-Borstel-Riems
Coordinator Bridging Topic "Diagnostics"
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Location

Bonn - Köln

Research areas
Contact person
Prof Achim Hörauf: Coordinator of the consortium "Neglected tropical diseases" at DZIF.

Prof. Dr. Achim Hörauf

University Hospital Bonn
Deputy Partner Site Speaker Bonn-Köln
Deputy Coordinator "Malaria and Neglected Tropical Diseases"
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Location

Hannover - Braunschweig

Research areas
Contact person
Silke Hartmann

Dr. Silke Hartmann

Hannover Medical School
Partner Site Manager Hannover-Braunschweig
Project Manager "Community-Acquired Infections at Mucosal Interfaces"
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München Tübingen Heidelberg Gießen – Marburg – Langen Bonn – Köln Hannover – Braunschweig Hamburg – Lübeck Borstel – Riems