CD4 T lymphocytes form a subgroup of T lymphocytes that is responsible for cell-mediated immune responses.
Synonyms
T helper cell
CD4 cells
Detailed description
T lymphocytes carrying the surface antigen CD4 are called T helper cells. After activation, they release substances that are either involved in cell-mediated immunity or that stimulate B cell immune responses. HIV infects mainly this T lymphocyte subgroup.
Andreas Moosmann’s research group investigates the immune system’s responses to viruses, particularly T cell responses. Widespread viruses such as the Epstein-Barr virus and the cytomegalovirus are at the core of their interest. After infecting healthy individuals, these viruses often remain in the ...
Primary human liver cells are required in order to investigate infections of the liver and to conduct preclinical tests of new agents. Isolating them from patient samples is a technologically challenging process requiring the highest levels of skill. This skill is available at the “Primary Human ...
The research group led by Dr. Angelika Riemer has set itself the goal of developing a functional therapeutic vaccine against human papillomavirus (HPV) infections and against HPV-induced tumors. While prophylactic vaccines induce the production of antibodies to prevent an infection with the pathogen ...
Salt could be a key factor in allergic immune reactions. A team working with DZIF professor Christina Zielinski at the Technical University of Munich (TUM) has demonstrated in cell cultures that salt
