CD4 T lymphocyte | German Center for Infection Research

Short description

CD4 T lymphocytes form a subgroup of T lymphocytes that is responsible for cell-mediated immune responses.

Synonyms

T helper cell

CD4 cells

Detailed description

T lymphocytes carrying the surface CD4 are called T helper cells. After activation, they release substances that are either involved in cell-mediated immunity or that stimulate B cell immune responses. infects mainly this T subgroup.

Nov 2018

Proc Natl Acad Sci U S A

Relationship between intact HIV-1 proviruses in circulating CD4(+) T cells and rebound viruses emerging during treatment interruption

Autoren

Lu CL et al.

Nov 2018

EMBO Mol Med

In vivo generation of human CD19-CAR T cells results in B-cell depletion and signs of cytokine release syndrome

Autoren

Pfeiffer A et al.

Nov 2018

Sci Rep

Author Correction: Differential expression pattern of co-inhibitory molecules on CD4(+) T cells in uncomplicated versus complicated malaria

Autoren

Abel A et al.

Feb 2017

Proc Natl Acad Sci U S A

Vpx overcomes a SAMHD1-independent block to HIV reverse transcription that is specific to resting CD4 T cells

Autoren

Baldauf H-M et al.

Oct 2018

FEMS Microbiol Lett

Bacterial type III secretion systems: a complex device for the delivery of bacterial effector proteins into eukaryotic host cells

Autoren

Wagner S et al.

Sep 2018

Eur J Immunol

Immunogenic cell death of dendritic cells following modified vaccinia virus Ankara infection enhances CD8(+) T cell proliferation

Autoren

Tappe KA et al.

Sep 2018

AIDS Res Hum Retroviruses

Short Communication: Tracking Tregs: Translocation of CD49b/LAG-3+ Type 1 T Regulatory Cells to the Gut-Associated Lymphoid Tissue of HIV+ Patients

Autoren

Augustin M et al.

Aug 2018

PLoS Pathog

SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue

Autoren

Kmiec D et al.

Doctor and data guru at the DZIF

Jörg Janne Vehreschild started his professional career as a programmer. However, he soon decided to pursue his second passion and began his medical studies a year later. Today, at only 39, Vehreschild

Between hospital and research

Christina Zielinski always wanted to become a doctor, but then research got hold of her, or, more precisely, human T cells did. Christina Zielinski has been focusing on these major players in the