CD4 T lymphocytes form a subgroup of T lymphocytes that is responsible for cell-mediated immune responses.
Synonyms
T helper cell
CD4 cells
Detailed description
T lymphocytes carrying the surface antigen CD4 are called T helper cells. After activation, they release substances that are either involved in cell-mediated immunity or that stimulate B cell immune responses. HIV infects mainly this T lymphocyte subgroup.
Epstein-Barr virus (EBV) prevents infected cells from being attacked by the immune system. The virus drives production of small molecules, so-called microRNAs, that suppress alarm signals sent out by
Some HIV-infected – and untreated children – who do not develop AIDS, control the virus in a different way from the few infected adults who remain disease-free. Scientists at LMU´s Max von Pettenkofer
DZIF scientists at the Heidelberg University Hospital developed a virus blocker against hepatitis B and D, which has been successful in two clinical trials
There are four globally endemic human coronaviruses which, together with the better known rhinoviruses, are responsible for causing common colds. Usually, infections with these viruses are harmless to
DZIF researchers have discovered that a protein which is well known for its role as a tumor suppressor is also required for inhibition of the replication of the coronavirus that causes SARS. The
In a clinical trial at the German Center for Infection Research (DZIF), leukaemia patients are being administered specially purified immune cells, so-called memory T cells, for the first time after a
Today’s World Hepatitis Day sets an ambitious goal: to eliminate viral hepatitis, especially hepatitis B and C, from the planet by 2030. Germany has also joined this international campaign. Scientists
A team of researchers from the Heinrich Pette Institute and the USA have succeeded in identifying a protein called HLA-F which functions as the ligand of an activating natural killer cell receptor
Providing a new paradigm to hepatitis B understanding, researchers at the German Cancer Research Center (DKFZ), the Heidelberg University Hospital and the German Center for Infection Research (DZIF)
DZIF scientists at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) have succeeded in identifying and targeting problematic pathogens in biofilms more rapidly. The biofilm adhesion
