CD4 T lymphocytes form a subgroup of T lymphocytes that is responsible for cell-mediated immune responses.
Synonyms
T helper cell
CD4 cells
Detailed description
T lymphocytes carrying the surface antigen CD4 are called T helper cells. After activation, they release substances that are either involved in cell-mediated immunity or that stimulate B cell immune responses. HIV infects mainly this T lymphocyte subgroup.
In a treatment centre in Guinea, DZIF researchers from the Heinrich Pette Institute (HPI) and the Bernhard Nocht Institute (BNITM) have, for the first time, identified the human immune response in
An international research group has identified a cellular factor of the human cell that is indispensable to the replication of Human Immunodeficiency Virus (HIV-1). Scientists of the Paul-Ehrlich
Many viral diseases tend to become chronic - including infections with the HI virus. Scientists from the DZIF site Bonn-Köln and from the TU München have now identified an immune factor which is
Researchers at the Heinrich Pette Institute, Hamburg, and at the Dresden Technical University (TUD) succeeded in developing a designer enzyme that is capable of specifically removing the provirus from
Patients infected with HIV have several benefits if they are treated with antiviral medication earlier than has been usual up to now: for a start, the severe AIDS-related complications occur less
Many viruses store their hereditary information in ribonucleic acid, RNA for short. Viral RNA is very similar to that of humans. However, the human immune system can differentiate between viral
According to figures of the World Health Organization, some 8.7 million people contracted tuberculosis in 2012 and this disease is fatal for approximately 1.3 million people throughout the world each
In the DZIF, scientists from the universities of Tübingen, Münster and Munich join forces and prepare together with the company Hyglos clinical studies on an active substance against the dreaded
(26/11/2014) Virologist Stephan Urban from the University of Heidelberg will receive the DZIF Prize for Translational Infection Research, worth 5000 Euros. It will be awarded for the first time at the
The German Center for Infection Research (DZIF) has initiated a consortium to strengthen Ebola research and close the knowledge gaps as quickly as possible in the fight against the epidemic. This
