Computational systems biology of infections and antimicrobial-resistant pathogens

Andreas Dräger's research group is dedicated to computational systems biology with a focus on infections and antibiotic-resistant pathogens. A primary goal is deriving model-driven new hypotheses with which increasing antibiotic resistance can be systematically combated. The group, which is based at the Institute of Biomedical Informatics at the University of Tübingen, works closely with partners from the nearby Institute of Microbiology and Infection Medicine. Their goal is to systematically elucidate the molecular processes in the human nose through which many bacteria enter the body. Which organisms are present in this microbiome, and how do they influence each other? The group's work includes the reconstruction of biological systems, their mathematical modeling, the standardization of these models, the development of specialized software solutions, and the application of machine learning methods.