Welcome to the DZIF -

the German Center for Infection Research

Research Areas

DZIF is doing research in nine areas:

Community-Acquired Infections at Mucosal Interfaces

Hepatitis

HIV

Infections of the Immunocompromised Host

Healthcare-Associated Infections

Malaria and Neglected Tropical Diseases

Emerging Infections

Novel Antibiotics

Tuberculosis

News

News and Press Releases:

Research environment with fermentation equipment: A scientist wearing a lab coat works at a table in a highly technical laboratory with stainless steel bioreactors, piping, and control systems.
© HZI/Frank Surup

Technology transfer for Corallopyronin A successfully completed with Phyton Biotech

Nanopore DNA sequencing of a patient sample.
© Katrina Friese

Metagenome-based rapid diagnostics for urinary tract infections could reduce antibiotic consumption

Urinary tract infections are among the most common reasons for prescribing antibiotics. Since conventional pathogen identification in the laboratory usually takes two to three days, initial treatment
Adult mosquitoes of the species Anopheles stephensi
© BNITM/Dino Schachten

Powerful medicines against malaria resistance: New drug combinations prove safe, well tolerated, and effective

Most malaria drugs are combination therapies based on artemisinin, an active ingredient derived from the medicinal plant Artemisia annua (sweet wormwood). The malaria parasite Plasmodium falciparum is
The photo shows a healthcare professional wearing a mask and gloves. She is pointing to nodules under the skin on a patient's bare upper body. A stylized sun and the title “World NTD Day” are displayed in white.
© KCCR/Jubin Osei‐Mensah/WHO

World Neglected Tropical Diseases Day on January 30

The World Neglected Tropical Diseases (NTD) Day on January 30 aims to raise awareness of diseases that affect millions of people worldwide but are usually overshadowed by other global health issues
Three small refrigerated glass bottles with labels indicating their contents.
© UKE/Leonie Mayer

Preparedness for future pandemics: MERS vaccine candidate shows long-lasting immune response

A new study has shown for the first time that an experimental vaccine against Middle East Respiratory Syndrome (MERS) induces a stable and functional immune response in humans that persists for at
All news

World Neglected Tropical Diseases Day on January 30

> than 1 billion people worldwide at risk

Researchers from the German Center for Infection Research (DZIF) and its African Partner Institutions are working to improve the diagnosis and treatment of neglected tropical diseases (NTDs).

Press release for World NTD Day
Graphic teaser for World NTD Day on 30 January featuring an orange background, a stylised white sunburst circle, and the wording ‘World NTD Day – Neglected Tropical Diseases’.
© WHO

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Research in Focus

Hamburg - Lübeck - Borstel - Riems

Clinical Tuberculosis Center

The Clinical Tuberculosis Center provides the expertise and infrastructure for the optimization, prevention, diagnosis, and treatment of tuberculosis (TB) as well as for translating research results into clinical practice. The main objectives of the Clinical Tuberculosis Center include coordinating clinical research activities involving the DZIF TB cohort. This cohort includes [...]

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Hannover - Braunschweig | Heidelberg | München | Tübingen

Transplant Cohort

Medical data and biological samples obtained from transplant patients are collected and managed across Germany with the help of the DZIF Transplant Cohort. The data and samples form the basis of scientific studies which investigate the connections between numerous factors influencing an organ’s susceptibility to infection and organ function. By [...]

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Tübingen

New strategies for specific eradication of Staphylococcus aureus

In this project, the scientists develop genetically engineered phage lysins and specific bacteriocins for the elimination of hospital germs such as Staphylococcus aureus, they clarify mechanisms of potential resistance mechanisms, and they analyse whether broad-spectrum or specifically acting agents have a more effective and lasting effect on colonization by [...]

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Hannover - Braunschweig

Preclinical development of Amidochelocardins

The challenge of antibiotic drug development today is the discovery and optimisation of novel bioactive compounds that do not show cross-resistances with clinically applied antibiotics, ideally due to a novel mode of action (MoA) which adresses unexploited microbial targets. In the case of chelocardin, this antibiotic substance was identified several [...]

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Our Partner Sites

Location

Bonn - Köln

Research areas
Contact person
Prof Achim Hörauf: Coordinator of the consortium "Neglected tropical diseases" at DZIF.

Prof. Dr. Achim Hörauf

University Hospital Bonn
Deputy Partner Site Speaker Bonn-Köln
Deputy Coordinator Malaria and Neglected Tropical Diseases
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Location

Hannover - Braunschweig

Research areas
Contact person
Silke Hartmann

Dr. Silke Hartmann

Hannover Medical School
Partner Site Manager Hannover - Braunschweig
Project Manager Community-Acquired Infections at Mucosal Interfaces
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Location

Hamburg - Lübeck - Borstel - Riems

Research areas
Contact person
Nicole Fischer

Prof. Dr. Nicole Fischer

University Medical Center Hamburg-Eppendorf
Deputy Partner Site Speaker Hamburg-Lübeck-Borstel-Riems
Coordinator Bridging Topic "Diagnostics"
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München Tübingen Heidelberg Gießen – Marburg – Langen Bonn – Köln Hannover – Braunschweig Hamburg – Lübeck Borstel – Riems