Healthcare-associated and Antibiotic-resistant bacterial Infections

Andreas Dräger's research group is dedicated to computational systems biology with a focus on infections and antibiotic-resistant pathogens. A primary goal is deriving model-driven new hypotheses with which increasing antibiotic resistance can be systematically combated. The group, which is based at the Institute of Biomedical Informatics at the University of [...]

The clinical research unit led by Prof. Evelina Tacconelli combines the information from clinical, microbiological and basic research. Scientists and physicians are working closely together to tackle the problem of increasing antibiotic-resistant germs in hospitals. Samples are collected in clinical trials, and the distribution of various multiresistant bacteria is investigated. [...]

Fabian Grein’s research group investigates new target structures (or targets) for antibiotics against Staphylococci. Infections caused by Staphylococcus aureus pose a serious threat to patient health as the virus is highly virulent and resistant to many antibiotics. From a medical perspective, it would be worthwhile developing specific narrow spectrum antibiotics. [...]

Matthias Willmann’s research group focuses on intelligent surveillance and intervention strategies for the prevention and further spread of multidrug-resistant pathogens in hospitals. The scientists combine modern molecular epidemiology techniques, such as “next generation sequencing”, with clinical epidemiology tools and mathematical modelling. In this way, they develop methods to recognise pathogen [...]