At Bonn - Cologne a concentration of activities has been achieved in relation to the research and development of new antibiotics. In cooperation with the Product Development Unit and the BfArM, the preclinical development of the new antibiotic corallopyronin A remains the top priority. In the vaccine research, vaccines against bacterial pathogens like S. aureus and A. baumannii are developed into the clinical application phase. Scientits in the research field "Healthcare-associated and Antibiotic-resistant bacterial Infections" research bacterial colonisations and infections with multidrug- resistant bacteria with regard to both type and prevalence, as well as treatment options and the effectiveness of infection control measures. In HIV research, the scientists bring new antibody mediated treatment approaches into translation. This site also coordinates the DZIF Clinical Trial Unit.