Glossary

C

Clinical phase

The clinical phase is a phase in drug development, in which the substance is tested in humans.

Co-infection

Co-infection is the simultaneous infection of a host with more than one pathogen .

Cohort

In the medical sense, a cohort is a group of patients with comparable symptoms or other similarities, which is observed over a certain period of time. The transplant cohort, a project within DZIF, provides data and biospecimen from transplant patients for studies.

Colistin

Colistin is an antibiotic of last resort.

Controlled human malaria infection model

In the controlled human malaria infection model, the disease is triggered in a controlled manner to test therapies and vaccines.

Corallopyronin A

Corallopyronin A is a natural compound antibiotic. It is effective against Gram-positive bacteria and intracellular Gram-negative bacteria.

Coronavirus

Coronaviruses are a family of RNA viruses that can infect both animals and humans. In humans they mainly cause respiratory tract diseases. They can run like harmless colds, but can also be fatal.

COVID-19

This disease is caused by the new coronavirus SARS-CoV-2, which was first identified in December 2019. COVID-19 primarily affects the respiratory tract, but can also cause damage to other organs. The disease can progress almost without symptoms or like a harmless cold. Especially in high-risk groups, COVID-19 can lead to severe courses with pneumonia and acute lung failure.

Crimean Congo haemorrhagic fever

Crimean Congo haemorrhagic fever (CCHF) is a viral infection with high mortality, which is mostly transmitted by ticks.

CRISPR-Cas9

CRISPR-Cas9 is a genome editing tool that allows cutting DNA at the sequence of choice. It offers new opportunities for the therapy of viral diseases.